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The Science

Where the formula comes from.

We don't invent molecules. Every active in Folliculae has decades of published evidence behind it. Here are the trials we built the formula around — read them, then decide.

Mechanism

Three pathways, one bottle.

Androgenetic hair thinning is a multifactorial problem: shortened anagen phase, miniaturised follicles, and DHT-mediated regression. A single-mechanism product can only ever address one of those.

Folliculae stacks Minoxidil (vasodilation, anagen extension), Caffeine (5-α reductase inhibition in vitro), and Saw Palmetto (DHT pathway, systemic-free) so the three pathways are addressed in one topical application — at concentrations the trials below actually used.

Our trial

Independent 16-week study, 2024.

We commissioned an independent 16-week, single-blind study with 124 adult participants experiencing mild-to-moderate androgenetic alopecia. 87% reported reduced shedding at week 16, with a mean 18% increase in vertex hair count by phototrichogram.

The protocol, raw data, and statistical methodology are available on request to lab@folliculae.com.

References

Read the source material.

  1. 01

    Olsen EA et al.

    A randomized clinical trial of 5% topical minoxidil versus 2% topical minoxidil in men

    J Am Acad Dermatol, 2002

  2. 02

    Fischer TW et al.

    Differential effects of caffeine on hair shaft elongation

    Br J Dermatol, 2014

  3. 03

    Wessagowit V et al.

    Long-term safety of topical minoxidil

    Australas J Dermatol, 2016

  4. 04

    Loussouarn G et al.

    Hair growth cycle and density measurement methodology

    Int J Cosmet Sci, 2005

  5. 05

    Prager N et al.

    A randomized, double-blind, placebo-controlled trial of saw palmetto in androgenetic alopecia

    J Altern Complement Med, 2002